Kirsten Silvey

My research interests lie in the role of protein structure in disease states. During my first rotation in the Lomas lab, I am looking at polymer formation of alpha-1 antitrypsin. Using negative stain electron microscopy and SEC-SAXS I am investigating alpha-1 antitrypsin interactions with a polymerisation inducing antibody in the hope to gain insight into the mechanisms of anti-trypsin polymerisation. I am excited to explore more structural techniques, such as NMR, in future lab rotations.