Paper published by Heather Cross in the journal: Annals of the Rheumatic Diseases

Research investigating childhood-onset systemic lupus erythematosus (cSLE) was conducted by George Robinson’s lab group and aimed to define Type I interferon (IFN) signalling and stratify the signatures of this signalling across cSLE. 

These findings linked IFN-related features to clinical phenotypes and showed distinct longitudinal outcomes for these patient groups. 

Link to paper: Type I interferon endotypes drive divergent clinical trajectories in childhood-onset SLE uncovered through a novel systems immunology approach - ScienceDirect