UCL Birkbeck MRC DTP

Fundamental Mechanisms of Disease

Understanding the fundamental mechanisms of disease can have a huge translational impact and we are internationally recognised in this area.

Research at UCL and Birkbeck to elucidate the Fundamental Mechanisms of Disease (FMD) leads the way internationally in both defining and solving the current and future challenges of 21st century biomedicine. The FMD theme is comprised from among 500 research groups, using multi-scalar cutting-edge technologies from the single molecule to the organismal level -  encompassing the integration of strategies (including molecular biology, developmental biology, stem cell  and regenerative medicine, immunology, genetics, pharmacology, structural biology, computational biology and biophysics) to answer fundamental questions and thereby enable as complete a picture of possible of the complex cellular events that underpin health and disease. The novel mechanistic insights achieved are simultaneously vigorously pursued towards translational outcomes. 

The Theme Directors are Professor John Christodoulou and Dr Ivana Bjedov. Their details can be found on the People page of this site.

Potential Supervisors

The UCL Birkbeck MRC DTP sends out a call for projects after we recruit our students and the full list of projects for the 2024/25 academic year will be available in the summer of 2024.

The list of projects for the 2023/24 academic year for the Fundamental Mechanisms of Disease theme is available. This list is indicative only. These projects may not be available in 2024/25